Response to “Sicker, Fatter, Poorer: The Urgent Threat of Hormone-Disrupting Chemicals to Our Health and Future” by Dr. Leonardo Trasande

To stay below ranges of exposure determined to be safe, consumers should read product labels closely and follow directions carefully. More

Updated OECD Test Guidelines Include Endocrine Endpoints

The OECD has updated test guidelines (TGs) on the 90-day, repeated dose oral toxicity study (408) and the prenatal developmental toxicity (PNDT) study (414) to ... More

Risk Communication About EDCs

Communication about risks from EDCs should employ the internationally recognized WHO/IPCS definition, and distinguish between mere endocrine activity and true disruption. More

OPINION: Endocrine disruption – converting a definition into regulatory action

The European Commission based its EDC criteria upon the WHO-IPCS definition. These have now entered into force and will start being applied to ongoing evaluations ... More

BPA Is An Endocrine Disruptor? Science says NOT!

The scope and magnitude of the CLARITY Core Study are unprecedented for BPA. If BPA were causing any adverse health effects, they likely would ... More

Endocrine disruptor assays go fast track

EPA is ramping up efforts to create high-throughput approaches for screening chemical effects on hormone synthesis and receptor pathways. More

A Rehash Of Flawed Chemical Exposure Cost Burden Estimates

The assigned disease burden costs are highly speculative and should not be considered in any serious policy discussions serving to protect public and regulate chemicals. More

US and Australia criticise EU’s proposed EDC restrictions

The US and Australia have complained to the WTO that hazard-based EU proposals to regulate endocrine-disrupting substances (EDCs) in biocidal and plant protection products will ... More

About The 2017 NAS Report On Endocrine Disrupting Chemicals And Low-Dose Effects

Low dose effects and NMDRs are often confused as they are frequently discussed together, e.g. in reference to the non-monotonic, low-dose hypothesis – the idea ... More

Lists of “Endocrine Disrupting” Chemicals Mislead Public

The French “official list” of EDCs officially undermines the scientific credibility of the French government’s approach to the endocrine issue. The public deserves better. More

Letter: Further thoughts on limitations, uncertainties and competing interpretations regarding chemical exposures and diabetes

Although disappointed, we are not surprised that Trasande’s response tries to avoid a serious discussion of legitimate scientific issues by accusing those who disagree with ... More

Estimates of human cost burden from exposure to endocrine-disrupting chemicals grossly exaggerated

The Endocrine Society published a series of economic papers in 2015 and 2016 that estimated annual health care costs attributable to EDC exposure in the ... More

Human cost of endocrine-disrupting chemicals exaggerated

Scientific impartiality must be mirrored in papers discussing endocrine disruptors say Gregory G. Bond and Daniel R. Dietrich. More

The current debate on cost burden by human exposure to endocrine disrupting chemicals

Recently, Gregory G. Bond from Northport, USA, and Daniel R. Dietrich from the University of Konstanz have contributed a comprehensive review about human cost burden ... More

Trasande-led human health impact and cost estimates attributed to endocrine disrupting chemical exposure completely unfounded, researchers show

Peer-reviewed paper published in Archives of Toxicology reports substantial shortcomings with underlying methodology, casual disregard of scientific principles More

Sensible And Pragmatic Proposal For Implementing The EC’s Criteria For Identifying Endocrine Disrupting Chemicals

The ECETOC proposal should be received favorably as it represents a sensible and pragmatic approach to what otherwise could be an overly complicated process. More

Publications result from SETAC workshop on endocrine active substances

To try to reach a consensus on appropriate approaches for establishing environmental safety for endocrine active substances, the Society of Environmental Toxicology and Chemistry (SETAC) ... More

Is America’s Sperm Crippled by Chemicals?

Following the lead of a New York Times article, numerous headlines have emerged blaming endocrine disrupting chemicals (EDCs) as the source of an emerging male ... More

Current test methods detect endocrine-disrupting chemical potential

Collectively, existing test methods are fully capable of detecting and characterizing potential adverse effects – whether directly due to interacting with the endocrine system, effects ... More

The Trouble Lies Not In Our Sperm, Poor Nick

The New York Times’ Nicholas Kristof plays up a non-existent threat to sperm from trace exposures in the environment. More

Letter to the Editor: Limitations, uncertainties and competing interpretations regarding chemical exposures and diabetes

The Trasande et al paper fails to meet standards for good practices in scientific reporting: stating the limitations of the underlying data, clearly articulating uncertainties, ... More

A Critical Review Of Flawed Claims Made In AIM Declaration On EDCs

AIM makes a number of claims of health effects attributable to EDCs that are highly speculative – i.e., the evidence is hardly as convincing as ... More

Nature editorial ‘exploits public anxiety’ on endocrine disruptors


Endocrine science: Will the real “manufacturers of doubt” please stand up?

By blaming others for “manipulating the science,” the authors of the Le Monde op-ed may actually be pointing the finger at themselves. More

But, Who’s Really Manipulating The Science On Endocrine Disrupting Chemicals?

The EDCs debate is highly controversial and polarized with serious questions raised on both sides about exactly who is, in fact, manipulating the science. More

Science “Undisrupted” with U.S. Regulation of Endocrine Disrupting Chemicals

We hope that the EU will look at the U.S. system as a model with its own chemical regulation. Moving from a hazard-based approach to ... More

When Salt Is An Endocrine Disruptor, The Term Is Officially Meaningless

The Canadian Journal of Fisheries and Aquatic Sciences published a new study entitled, "Interactive effects of road salt and leaf litter on wood frog sex ... More

Exposure to EDCs in the U.S. and EU: What They’re Saying about the Alleged Health Care and Lost Earnings Cost Estimates

A series of recent economic analyses by Trasande et al. attempts to sound an alarm in both the U.S. and European Union over staggering health ... More

Do Endocrine Disruptors Really Cost Us Hundreds Of Billions?

It’s a scary prospect—everyday items are costing our country billions. Unfortunately, like many other headline-generating studies, this paper is based on flawed science. More

‘Hormone-Disrupting Chemicals’ Are Not A Global Health Scourge

Leonardo Trasende is an activist scientist, trotting out junk science at rapid speed to further his political, policy, and regulatory goals. That includes his latest, ... More

Headline Hype or Sound Science? New Study Claims U.S. Loses $340B a Year to Chemical-Related Health Problems

A recent study has been grabbing headlines with the claim that health issues related to chemical exposure could be costing the U.S. around $340 billion ... More

Time Magazine Promotes Superstitious Chemophobia

Time magazine is reporting a correlational study that claims to have sufficiently tortured the data, ah, quantified the economic harm that these estrogen-fueled epidemics is ... More

ACC Comments on Lancet Paper Alleging Significant U.S. Health Care Costs from Exposure to EDCs

Today’s release is the latest in a series of papers in which Dr. Trasande and his colleagues demonstrate a casual indifference toward scientific principles, yet ... More

ShiFt happens, but it’s not always good science

Rather than making discoveries that established science cannot explain, advocates are simply making new allegations, using unique interpretations that have already been rejected by established ... More

Pharma industry says EDC criteria need a risk-based approach

Sini Eskola, Director of Regulatory Affairs at the EFPIA, told Manufacturing Chemist that the industry welcomed the guidance and appreciated that the content was based ... More

Scientists Call for ‘Potency Comparisons’ in EDC Criteria

The European Commission's criteria for identifying endocrine disrupting chemicals (EDCs) should allow for potency comparisons with natural hormones and human pharmaceuticals, according to more than ... More

NIEHS 25 Year Celebration Of Endocrine Research — Some Progress, But An Even Greater Opportunity To Deliver Clarity

It would be helpful if NIEHS would publicly endorse EPA's EDSP program and the WHO/IPCS definition of an EDC and emphasize the importance of having ... More

ACC: NIEHS celebrates 25 years of endocrine disruptor research – we ask, what’s to celebrate?

Today, misinformation and public confusion over EDCs runs rampant, and a slew of products ranging from sunscreen to plastic food containers are potentially at risk ... More

An appeal for the integrity of science and public policy

We, scientists and signatories of this appeal assert our concern for the erosion of scientific principles in the purported validation of experimental evidence, which is ... More

Endocrine disruptors: science is more potent than politics

A large group of scientists from across various sectors are supporting an appeal to the European Commission regarding its proposed regulation to establish criteria for ... More